Typhoid and Paratyphoid in recent Global Burden of Disease Articles

CaT Secretariate would like to draw your attention to the Global Burden of Disease Study 2010 study, published last month in The Lancet.  Two of the seven articles in the series are attached, which highlight the estimated burden of typhoid and paratyphoid fevers in the world .                                                                                                                 

The Global Burden of Disease Study 2010  estimates that in 2010 there were:

-  190,200 deaths from typhoid and paratyphoid fevers,  and

-  12,239,000 DALYs lost as a result of typhoid and paratyphoid fevers.                                                                                                                                                                                

The Lozano paper indicates:

·         All ages deaths from typhoid and paratyphoid fevers (thousands)

1990: 136.5 (16.5–254.7)  2010: 190.2 (23.8–359.1)  %Ä: +39.4%

·         Age-standardized death rates from typhoid and paratyphoid fevers (per 100 000)

1990 2.4 (0.3–4.4)             2010: 2.7 (0.3–5.1) %Ä: +15.5%

·         Typhoid and paratyphoid fevers caused 1.5% of global deaths in 1-4 year olds of both sexes combined in 2010

·         Typhoid and paratyphoid fevers caused 1.1% of global deaths in 15-49 year old females in 2010

·         Typhoid and paratyphoid fevers caused 0.9% of global deaths in 15-49 year old males in 2010

·         Globally, typhoid and paratyphoid together are the 35th leading cause of years of life lost, with the highest burden in Asia and sub-Saharan Africa


The Murray paper indicates:

·         All ages DALYs lost from typhoid and paratyphoid fevers (thousands)

1990: 9256 (1281–17 123)  2010: 12,239 (1702–23,043)  %Ä: +32.2%

·         DALYs lost from typhoid and paratyphoid fevers (per 100 000)

1990 175 (24–323)  2010: 178 (25–334)  %Ä:+ 1.7%

·         Globally, typhoid and paratyphoid together are the 52nd leading cause of years of DALYs lost, with the highest burdens in Asia and sub-Saharan Africa


Executive summary

The Global Burden of Disease Study 2010 (GBD 2010) is the largest ever systematic effort to describe the global distribution and causes of a wide array of major diseases, injuries, and health risk factors. The results show that infectious diseases, maternal and child illness, and malnutrition now cause fewer deaths and less illness than they did twenty years ago. As a result, fewer children are dying every year, but more young and middle-aged adults are dying and suffering from disease and injury, as non-communicable diseases, such as cancer and heart disease, become the dominant causes of death and disability worldwide. Since 1970, men and women worldwide have gained slightly more than ten years of life expectancy overall, but they spend more years living with injury and illness.


GBD 2010 consists of seven Articles, each containing a wealth of data on different aspects of the study (including data for different countries and world regions, men and women, and different age groups), while accompanying Comments include reactions to the study's publication from WHO Director-General Margaret Chan and World Bank President Jim Yong Kim. The study is described by Lancet Editor-in-Chief Dr Richard Horton as "a critical contribution to our understanding of present and future health priorities for countries and the global community."

- Posted By IPA Admin Office on Date (MM/DD/YYYY) : 01/07/2013


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